These sdss are designed to provide essential information. Penta contains trace amounts of hexa, hepta, and octochlorodibenzopdioxins, hexa, hepta, and. Mitogenic and cytotoxic effects of pentachlorophenol to aml. Other longterm effects pentachlorophenol may damage the liver and kidneys.
Section 1 chemical product and company identification. For both pentachlorophenol and tetrachlorohydroquinone, sulfates accounted for 90% or more of the total conjugates. At one point, penta was the most widely used preservative but concerns. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and. Do not administer aspirin, phenothiazines, or atropine since they may enhance toxicity. A 1984 report cites the measured concentration of pentachlorophenol in the indoor air of pressuretreated log homes brushed with pentachlorophenol in the range of 0. Do not breathe dust at concentrations greater than the exposure limits. Exposure to penta during pregnancy should be avoided.
Sep 23, 2003 material safety data sheet pentachlorophenol treated wood section 1 identification manufacturers name. University, michigan state university, cornell university, and the university of idaho. Rapid assay pentachlorophenol msds 3 applicable exposure limits sulfuric acid osha pel 1 mgm 3 acgthtlv 1 mgm 3 1,2,6trihydroxyhexane txds. Pentachlorophenol and byproducts of its synthesis national. There is limited evidence that pentachlorophenol is a teratogen in animals.
Com, is a premium domain for sale now in a flippa auction. It is a restricted use pesticide rup in its formulations as a wood preservative, but a general use. Material safety data sheet pentachlorophenol msds section 1. Pentachlorophenol pcp is an organochlorine compound used as a pesticide and a disinfectant. Pentachlorophenol 87865 hazard summary pentachlorophenol was once one of the most widely used biocides in the united states, but it is now a restricted use pesticide and is no longer available to the general public. Male and female mice evaluated by the national toxicology program were fed up to 400 ppm technical. Material safety data sheet pentachlorophenol sc257975 hazard alert code key. Penta is highly effective against fungi and insects but not against marine borers. Overexposure to pentachlorophenol could result in injury, illness, or even possibly death.
The occupational safety and health administrations osha hazard communication standard 29 cfr 1910. Studies on the physiology of microbial degradation of. Disposal considerations dispose of waste and residues according to agreement with local authorities. The msds says, pentachlorophenol has been found to have toxic effects in laboratory animals. Possible cancer hazard may cause cancer based on animal data. The protocol was approved by the weill cornell medical college. Osha table z1 limits for air contaminants 29 cfr 1910. Forced diuresis may be effective to reduce total body burden. Creosote, pentachlorophenol and inorganic arsenicals. A method for reducing contaminants during synthesis of pentachlorophenol includes providing a phenolbased starting material and a catalyst, which form a reaction mixture. The number in parentheses is the metric equivalent in kilograms. Skin designation pentachlorophenol cas 87865 can be absorbed through the skin. Material safety data sheet pentachlorophenol 62899 page 2 of 7 chloracne in humans, the absorption of pentachlorophenol by any route may result in the development of the skin condition, chloracne. Simultaneous determination of pentachlorophenol, niclosamide.
Issues can be raised to the cornell chemical hygiene officer if further action is. General product information pentachlorophenol has been evaluated for possible cancer causation in laboratory animals. Data are presented as proportions, means with standard deviations sds, and. Pentachlorophenol is a manufactured chemical that does not occur naturally. Pentachlorophenol is broken down by sunlight, other chemicals, and microorganisms to other chemicals within a couple of days to months. Material safety data sheet pentachlorophenol treated. This website and underlying databases are maintained and updated by pesticide action network north america pan. Pentachlorophenol or penta was developed in the 1930s as one of the first synthetic organic wood preservatives. Until further testing has been done, it should be treated as a possible teratogen in humans.
You can search both the pdf and webbased versions of the laboratory safety manual using. Ecological soil screening levels for pentachlorophenol. Pdf determination of pentachlorophenol in drinking water. Epa list of inerts ncap inerts report pdf historic uses in the u. Chronic longterm exposure to pentachlorophenol by inhalation in humans has. Pentachlorophenol cas 87865 can be absorbed through the skin. The first number under the column headed rq is the reportable quantity in pounds. This product is a clear colorless to yellow liquid and is odorless.
As a wood preservative, pentachlorophenol acts as both a fungicide and insecticide freiter, 1978. The miscellaneous mill uses primarily involve the application of pentachlorophenol as a slime reducer in paper and pulp milling and may constitute. Material safety data sheet rapid assay pentachlorophenol. May 19, 20 pentachlorophenol is an organochlorine compound, which is a white needlelike crystal.
Msds sds material safet data sheetsafety data sheet niosh national institute for occupational safety and health ntp national toxicology program pahs polycyclic aromatic hydrocarbons pcp abbreviation for pentachlorophenol pd4 position document 4 for the wood preservative pesticides. From the 1950s to the late 1980s pentachlorophenol based fungicides were widely used in the new zealand sawmill industry, and there were persistent claims of longterm adverse effects on health. Pentachlorophenol pressure treated woodpolespiling 1. The solubility of pentachlorophenol pcp is 35 mgl in water at 50c. Pentachlorophenol is extremely toxic to humans from acute shortterm ingestion and. Bottom sediment sludge from the treatment of wastewaters from wood preserving processes that use creosote andor pentachlorophenol. Pentachlorophenol is widely distributed throughout the skagerrak.
Trade names for pentachlorophenol include dowicide, pcp, penchlorol, penta, penta plus, pentachloral, pentacon, penwar, priltox, santobrite, santophen, sinituho, and weedone regulatory status. Material safety data sheet pentachlorophenol treated wood. A chlorine flow is introduced so that it is in contact with the reaction mixture, and the starting material and chlorine are reacted via a temperatureprogrammed reaction. It can be found as pure pcp, or as the sodium salt of pcp, the latter of which dissolves easily in water. The chemical ingredients in this material are in the section. As a bonus 26 additional hazard domains are included in the portfolio. Concentrations in excess of 1 mgm3 can cause upper pentachlorophenol treated wood revision 8820 bell lumber and pole company page 1 of 5. Skin potential significant contribution to overall exposure by the cutaneous r oute 0.
Identification product identifier kmg penta blocks other means of identification product code epa reg. Not required to be updated every three years whmis 1992, b40, section 29,2 prepared by. Pentachlorophenol is readily absorbed through the skin, causing irritation. Pentachlorophenol reportfinal draft for public comment. This product is now cancelled, when it was registered it was used for the following. Technical grade pentachlorophenol is readily absorbed through the skin. Material safety data sheet, per the requirements of the osha hazard communication standard 29 cfr 1910. Department of health and human services public health service agency for toxic substances and disease registry. May 21, 20 material safety data sheet pentachlorophenol msds section 1. A portion of the dose was recovered in urine as tetrachlorohydroquinone 5% and its conjugates 15%.
Pentachlorophenol has been found to have toxic effects in laboratory animals. Its primary application has been as a wood preservative. First produced in the 1930s, it is marketed under many trade names. Buy high purity pentachlorophenol analytical standards from chem service inc. Pentachlorophenol an overview sciencedirect topics. See working with the information on this page section below for important notes about this data. Material safety data sheet according to eec directives 91155eec and 93112ec citofix powder 20000127 product name.
It enters the environment through evaporation from treated wood surfaces, industrial spills, and disposal at uncontrolled hazardous waste sites. Dieckmann research group safety information emergency telephone number. Questions regarding this safety manual or a users rights under the osha lab standard should be first directed to the cnf safety manager. Determination of pentachlorophenol residue in meat and fish. Pressure treated wood can cause irritation of the skin. Issues can be raised to the cornell chemical hygiene officer if further action is needed. It is located in appropriate sections based on the ansi z400. Pentachlorophenol penta or pcp was first introduced for use as a wood preservative in 1936 by dow chemical company and monsanto chemical company. A3 confirmed animal carcinogen with unknown relevance to humans. The use of company or product names is for identification only and does not imply endorsement by the.
Pentachlorophenol can be found in the air, water, and soil. Pentachlorophenol was primarily recovered in urine as glucuronide and sulfate conjugate metabolites. Monooxygenase activity was markedly induced by technical grade pentachlorophenol in a concn dependent pattern, with a maximum response of approx 14 fold seen at. Yes 27 hazard domains that include are in right now available in a online flippa 30 day auction. Rapid primary care followup from the ed to reduce avoidable. Exposure to treated wood should be kept to a minimum. Material safety data sheet pentachlorophenol treated wood section 1 identification manufacturers name. Laboratory safety manual cornell ehs cornell university. Extreme high moderate low section 1 chemical product and company identification product name pentachlorophenol statement of hazardous nature considered a hazardous substance according to osha 29 cfr 1910. Pentachlorophenol is a chlorinated aromatic compound that has been used extensively as a fungicide. Biotransformation of pentachlorophenol, aniline and biphenyl in isolated. Wood treating chemicals from kmg expand for description and associated downloads pentachlorophenol solution container type download datasheet duratreat 40 wood preserver bottle penta 5 sure treat wood protector wood preserver bottle penta ol technical pentachlorophenol bottle kmg is the sole supplier of eparegistered pentachlorophenol penta in north america. Cornell ehs has taken responsibility for maintaining an institutional chemical hygiene plan.
Morrell, in handbook of environmental degradation of materials second edition, 2012 14. Hepatocytes isolated from adult sprague dawley rats were incubated with analytical pentachlorophenol of 99% purity, technical grade pentachlorophenol, or its sodium salt, whic contains only minor concn of technical impurities. Impure pentachlorophenol the form usually found at hazardous waste sites is dark gray to brown and exists as dust, beads, or flakes. Pcp has historically been one of the most widely used biocides in the united states atsdr 2001. Material safety data sheet page 4 of 7 the following information on appropriate personal protective equipment is provided to assist employers in complying with osha regulations found in 29 cfr subpart i beginning at 1910. Pcp has been used as an herbicide, algaecide, defoliant, wood preservative, germicide, fungicide and molluskacide. The main sources of information for this fact sheet are epas. Pentachlorophenol was found in the liver, blood, and urine of those fatalities who had been exposed to pentachlorophenol and sodium salt mixture. The concentration level of other chlorinated phenolics is less than 1 ng1.
Pure pentachlorophenol exists as colorless crystals. The user must not remove, modify, obscure, or in any other way alter the content or readability of any safety labels or placards located on or inside the equipment. Toxic substances control act tsca, 40 cfr 710 the material is a mixture as defined by tsca. Chemical product and company identification product name. Untreated hepatocytes were compared to pcp treated hepatocytes to determine significant differences in stimulatory patterns. Such information can be found in the safety data sheet sds for the chemicals. Material safety data sheet page 2 of 7 emergency overview. Statement of basis for the issuance of draft air permit. The use of company or product names is for identification only and does not imply endorsement by the agency for toxic substances and disease registry. The school nurse should maintain copies of material safety data sheets. Us20090054699a1 method for reducing microcontaminants. Pentachlorophenol is a moderately toxic compound in epa toxicity class ii.
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